Neither CBDa nor CBD cause poisoning. Most cannabinoids, such as THC and CBD, bind to the cannabinoid receptors CB1 and CB2, but their other acid forms take a different approach. GW Pharma, the pharmaceutical company responsible for Epidiolex, has conducted studies comparing the effects of CBDA versus CBD. In some studies, the team found that CBDA may have better bioavailability and a faster acting effect than its original compound.
Both are not psychoactive, meaning that users don't get high or take drugs. This is because both CBD and CBDA don't directly interact with our endocannabinoid receptors. THC and CBD do what they do by binding to the cannabinoid receptors CB1 and CB2.They can only do so because they have been decarboxylated. This means that CBDA does not bind to those two receptors.
In contrast, CBDA appears to bind to more than half a dozen other receptors, particularly those related to the serotonergic system. Currently, a limited amount of data we have on CBDA indicates that it is not psychoactive. Like its decarboxylated counterpart, the CBDA will not place it. But it could help reduce stress and anxiety and, at the same time, offer some degree of pain relief.
Hopefully, the studies confirmed the current assumptions. Look for raw cannabis strains that are high in CBD to take advantage of the benefits of CBDA, which become even more potent when mixed with fruits and vegetables. THC-rich strains that have not yet been decarboxylated are likely to contain exceptional levels of CBDA. Find out how you can experience the benefits of CBDA and discover cannabis strains rich in this powerful acidic cannabinoid.
When the acid form is decarboxylated, CBDA is transformed into CBD, the active ingredient in many infusion products. Placing drops of CBDA oil under the tongue (sublingual administration) is the best way to ensure rapid and efficient absorption and minimize delays associated with digestion. In addition, certain studies have shown that CBDA prevents the growth and spread of cancerous tumors. In another study, the research team tested the effects of CBDA and ondansetron, an anti-nausea medication.
CBDA can help treat nausea, digestive problems, and anxiety, all of which are often comorbid (occur together). CBDA oil can be consumed or absorbed through tinctures, raw cannabis juice, topical creams, and raw CBDA oil. You'll get better results with lower doses when using CBDA products (or whole-plant hemp CBD products that contain CBDA) compared to pure or nearly pure CBD isolate. But there is another lesser-known cannabinoid called CBDA that is attracting the attention of consumers and the scientific community, as early findings show that even small amounts of CBDA can have significant beneficial physiological effects.
Healer Drops are whole plant hemp formulas with CBD, CBDA and the Healer spectrum of acidic and minor plant beneficial cannabinoids, terpenes, flavonoids and phytonutrients. CBDA oil, CBDA tincture, and CBDA drops refer to CBDA in a form that can be taken sublingually, added to food, or applied directly to the skin. But what does it actually do when you ingest it? The short answer is that we know much less about the effects of CBDA compared to the effects of CBD. In this study on animal models, CBDA showed “significantly greater potency in inhibiting vomiting in shrews and nausea in rats compared to CBD”.